IANAL but… Yeah, I think you have to be very careful if drawing in that situation.
The number one thing to consider is that defensive lethal force is only warranted when faced with a threat that will cause death or grave bodily harm. At this point, because most people survive just fine with mild symptoms I do not think it would qualify in most circumstances. Unless you were elderly or otherwise health compromised in some way.
I would compare it to a thrown punch. Generally, it is not considered lethal force because most people can take a hit or two without anything other than a bruise (unless there is a large disparity in force/skill). But if you punch an elderly person, even one punch can very much be a lethal so their rules of engagement might be different.
I’m not necessarily saying you can’t or shouldn’t, but be very clear on where your line is and how you would pass the “reasonable person” test for a judge/jury looking at the case weeks or months later.
This is one of the reasons I’ve added a less-than-lethal option to my carry these days. If someone coughs on me, they may not warrant getting shot but an assault like that is definitely going to get the hot-sauce in response. I’d apply similar assessment to a fight over TP or other supplies.