My perspective is that of a firearms hobbyist that reloads his own ammo and casts bullets for all of the centerfire calibers he reloads–rifle and pistol. (Bias alert/COMPLETED)
It is hard to fault the idea of a Ruger 10/22 as a first rifle. They do many things very well.
I “get” it about wanting more OOMPH, and using a Ruger PC-9 to achieve that end. A handgun cartridge in a long arm has some merit. It is a time-tested idea that has existed since cartridge arms came on stream c. 1873. Just keep in mind that A LOT of calibers have a lot more OOMPH than the 9mm has–that Rem 700 x 223 you spoke of is one such example. A bolt-action or semi-auto in 223 is no slouch as a first rifle either, and the 223 cartridge is SUPERBLY accurate at far longer ranges than any 9mm can muster. And, the 223 is considered something of a small rifle cartridge.
The late Townsend Whelen said it best–“The 30-06 is NEVER a mistake.”
I’ll suggest a book for you to buy before you plunk down significant dollars on a rifle–“Cartidges of the World”. It is in its 15th Edition, and it will give you a glimpse into the calibers available to you to accomplish the goals you are seeking, with comparisons on performances and capabilities. Best of luck on your search.