In general when you are at bad breath range the preferred option is to leave your gun/knife/etc. where they are and concentrate on Extreme Violence. Your primary focus should be to damage your attacker and break contact. Never punch a person in the face or head, go for the throat, it’s soft and squishy. If your hands are locked up, go for the feet or the knees with your foot, stomp on an arch, rake the knee cap, knee the groin. Swing your arms around windmill style to break your hands loose, you will have force and velocity on your side. If you get a hand free IMMEDIATELY go for the eyes with two fingers (A’La the Three Stooges but with just a bit more FEELING), THEN punch them in the throat. Don’t forget you have a forehead for head butts and teeth to bite anything you can sink them into. Unless you are exceedingly well trained in wrestling NEVER to to the ground with your opponent. If you feel yourself falling forwards or backwards LAUNCH your body in that direction and roll clear if you can.
If/When they go down BREAK CONTACT, run three to five strides away and then turn 90* for two more strides and employ your EDC to cover down. Do not close with them again if they are down, if they get up and come towards you, shoot them as many times as is necessary.
If you get in a knife fight where the both of you only have a knife you have already screwed up. There is only one Golden Rule in a knife fight. You WILL get cut or stuck.