Depends.
Some remanufacturers such as Black Hills and Hunter’s Shack Munitions (HSM) have excellent reputations.
Many do not.
In todays ammo world weirdness I wouldn’t mind shooting Hunter’s Shack Munitions----in fact I have a few boxes of.38 spls----for range work.
Never been disappointed.
I’d be wary of other remanufacturers though.
Heck I’m even wary of some new ammo manufacturers, like the once highly regarded Remington.
I’ve used reloads in the past. But only from freedom munitions & lax. Only at a range, mostly just to run my firearm, never had a problem with their ammo.
I have a buddy that has been shooting remanufactured ammo for years. We used to shoot at an indoor range that had questionable ventilation system. The people on either side of him always got plenty of low light training 
He was sighting in his AR at an indoor range yesterday. The bolt was not cycling at all. He had to use the charge handle to eject every shot. I suspected a blocked gas tube and/or gas key due to the ammo he runs. He gave me a call last night and said the gas block had come loose from the barrel, but boy it, the tube, and the key all need a lot of cleaning before he plans to put it back together. 
Won’t do reloads. Learned my lesson when I started shooting and bought 100 rds of .45 ACP at a range that had a nice price. Had a round that the bullet popped out of the case when I was loading into the magazine. That got set aside, (as well as the magazine which had unburnt powder in it.) Found 5 more out of the rest had bullets so lose I could pull them out of the shell. Out of the 94 left some failed to cycle the slide properly. Never again, unless I learn to hand load or reload myself, I have taken a couple of hand loading classes.
There probably a bulge in the brass it is a simple fix if you have the machine to do it is a bulge buster I run all my brass through it works great
I have shot thousands and thousands of reloads that I did myself when I was shooting competition. About the only way you could afford to go through 20,000 plus rounds a year! Even though I loaded them myself was careful paid attention and do quality control checks I once had a squib load that I was lucky to notice immediately and stop firing while I was going through an obstacle course.
Now that was one in 5000 rounds but could have been a disaster. Will I shoot reloads? Of course I reload myself so I do but I am always always cautious.
Remanufactured ammo is a crapshoot. Done correctly it’s a great resource-done incorrectly it can be of questionable quality (and even safety). I’ve shot literally thousands of my own reloads for decades -but I do my best to insure they are done correctly. For range ammo (or hunting ammo (lots and lots of varmint ammo over the years) it’s worked great. For a number of reasons I do NOT use reloads for carry. For accuracy or reliability testing it should be fine. You “may” experience an occasional issue with brass previously fired through another weapon. Check fired brass after shooting a few rounds OR after anytime a round sounds “different”. If you experience ANY FTF’s or see ANY signs of damaged brass (cracked cases/primers that have “flowed” or backed out STOP and dispose of remaining ammo. Funky or questionable ammo is not worth the risk.
Remanufactured ammo for SD? Heck yeah!
All my ammo is potentially SD ammo.
Besides the range, the remanufactured stuff is for when I can’t get factory fresh SD ammo
and during the last ammo shortage it wasn’t as far fetched as it sounds, but I always managed to have a box or two of good stuff even during the darkest of times
I’ve had absolutely no issues with HSM remanufactured ammo, but I’ve had plenty of grief from new Remington SD ammo (.38 spec.)
If I had to choose between the two, guess which one I’d pick?
Who’s doing a little checking this morning. Check for we manufacture ammo companies.
Two of the four had higher prices than what I can buy Federal from my usual supplier.
Two of the four have absolutely terrible reviews when you check outside their website for independent opinions. Not sure that it is worth a couple of bucks savings!
I think if it’s not my own reloads I’ll keep buying Federal
