I’ve had mine in for about a year with no noticeable permanent compression. But they’re also ridiculously inexpensive and they usually use a Velcro system that makes them easily interchangable.
A wedge made a big difference in carrying for me with a mostly sedentary job.
I’ve had one on my EDC 2 years now, and still Goin’ strong.
Just a follow up. Mastermind tactics wedge has been great. I like that I can adjust the foam in it. It’s comfortable. I also went with a shorter holster against some people’s advice (keel principal), but it was a game changer for me. 43x JM kydex (43x length not 48) mono clips with a mastermind pillow is the most comfortable and easy to take on and off set up I’ve ever had.
Gotta love it when a plan comes together.
“I’ve started using holster wedges recently, and honestly, they make a huge difference. They help tuck the grip in closer, reduce printing, and make AIWB way more comfortable for long wear. It’s one of those small upgrades that changes everything. Also came across this while browsing: https://cloudsterpillow.com/”
This happens sometimes don’t give up. G-d bless. Welcome to the community.
You know it! 
There are some new “pillow” style wedges that are very comfortable.
The ‘pillows’ that line the inside of helmets work pretty well.
HTH